publications
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In vivo bone marrow microenvironment siRNA delivery using lipid–polymer nanoparticles for multiple myeloma therapy
PNAS
Guimarães PPG, Figueroa-Espada C, Riley RS, et al.
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siRNA Lipid–Polymer Nanoparticles Targeting E-Selectin and Cyclophilin A in Bone Marrow for Combination Multiple Myeloma Therapy
Cellular and Molecular Bioengineering
Figueroa-Espada CG, Guimarães PPG, Riley RS, Xue L, Wang K, Mitchell MJ
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Lipid Nanoparticle Composition Drives mRNA Delivery to the Placenta
Preprint: doi: https://doi.org/10.1101/2022.12.22.521490
Rachel E. Young, Katherine M. Nelson, Samuel I. Hofbauer, Tara Vijayakumar, Mohamad-Gabriel Alameh, Drew Weissman, Charalampos Papachristou, Jason P. Gleghorn, Rachel S. Riley
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Overcoming the challenge of long-term storage of mRNA-lipid nanoparticle vaccines
Molecular Therapy (2022)
Rachel E. Young, Samuel. I Hofbauer, Rachel S. Riley
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ionizable lipid nanoparticles for in utero mrna delivery
Science Advances (2021)
Rachel S. Riley, Meghana V. Kashyap, Margaret M. Billingsley, Brandon White, Mohamad-Gabriel Alameh, Sourav K. Bose , Philip W. Zoltick, Hiaying Li, Rui Zhang, Andrew Y. Cheng, Drew Weissman, William H. Peranteau, Michael J. Mitchell
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exploiting the placenta for nanoparticle-mediated drug delivery during pregnancy
Advanced Drug Delivery Reviews (2020)
Christian Figueroa-Espada, Samuel Hofbauer, Michael J. Mitchell, Rachel S. Riley
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Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation
Journal of Controlled Release (2021)
Hamideh Parhiz, Jacob S Brenner, Priyal Patel, Tyler E Papp, Hamna Shahnawaz, et al.
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ionizable lipid nanoparticles encapsulating barcoded mrna for accelerated in vivo delivery screening
Journal of Controlled Release (2019)
Guimaraes PG, Zhang R, Spektor R, Tan M, Chung A, Billingsley MM, El-Mayta R, Riley RS, Wang L, Wilson JM, Mitchell MJ
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nanoparticles for nucleic acid delivery: applications in cancer immunotherapy
Cancer Letters (2019)
Mukalel A, Riley RS, Zhang R, Mitchell M
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delivery technologies for cancer immunotherapies: challenges and opportunities
Nature Reviews Drug Discovery (2018)
Riley RS, June C, Langer R, Mitchell M
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potent in vivo lung cancer wnt signaling inhibition via cyclodextrin-lgk974 inclusion complexes
Journal of Controlled Release (2018)
Guimaraes PG, Tan M, Tammela T, Wu K, Chung A, Oberli M, Wang K, Spektor R, Riley RS, Viana CT, Jacks T, Langer R, Mitchell MJ
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evaluating nanoshells and a potent biladiene photosensitizer for dual photothermal and photodynamic therapy of triple negative breast cancer cells
Nanomaterials (2018)
Riley RS*, O’Sullivan RK*, Potocny AM, Rosenthal J, Day ES
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photochemotherapeutic properties of a linear tetrapyrrole palladium(ii) complex displaying an exceptionally high phototoxicity index
Inorganic Chemistry (2018)
Potocny AM*, Riley RS*, O’Sullivan RK, Day ES, Rosenthal J
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layer-by-layer assembled gold nanoshells for the intracellular delivery of mir-34a
Cellular and Molecular Bioengineering (2018)
Goyal R, Capadia CH, Melamed JR, Riley RS, Day ES
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evaluating the mechanisms of light-triggered sirna release from nanoshells for temporal control over gene regulation
Nano Letters (2018)
Riley RS, Dang M, Billingsley MM, Abraham B, Gundlach, L, Day ES
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advances in targeted nanotherapeutics: from bioconjugation to biomimicry
Nano Research (2018)
Valcourt DM, Harris J, Riley RS, Dang M, Wang J, Day ES
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frizzled7 antibody-functionalized nanoshells enable multivalent binding for enhanced wnt signaling inhibition in triple negative breast cancer cells
Small (2017)
Riley RS, Day ES
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antibody-nanoparticle conjugates to enhance the sensitivity of elisa-based detection methods
PLoS ONE (2017)
Billingsley MM, Riley RS, Day ES
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gold nanoparticle-mediated photothermal therapy: applications and opportunities for multimodality cancer treatment
WIREs Nanomed Nanobiotechnol (2017)
Riley RS, Day ES
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quantification of sirna duplexes bound to gold nanoparticle surfaces
Biomedical Nanotechnology: Methods and Protocols (2017)
Melamed JR, Riley RS, Valcourt DM, Billingsley MM, Day ES
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using gold nanoparticles to disrupt the tumor microenvironment: an emerging therapeutic strategy
ACS Nano (2016)
Melamed JR, Riley RS, Valcourt DM, Day ES
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elucidating the fundamental mechanisms of cell death triggered by photothermal therapy
ACS Nano (2015)
Melamed J*, Edelstein R*, Day ES.
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enzyme-linked immunosorbent assay to quantify targeting molecules on nanoparticles
Methods in Molecular Biology (2018)
Riley R*, Melamed J*, Day ES
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dtaf dye concentrations commonly used to measure microscale deformations in biological tissues alter tissue mechanics
PLoS ONE (2014)
Szczesny S, Edelstein R, and Elliott D.